The main purpose of the following paper is comparative presentation of the forecasts of occupational structure of employment in Poland conducted by Cedefop and obtained within the labour demand forecasting system (LDFS) in Poland. LDFS is an expert interactive system that allows analysis and forecasting of time-series-cross-section economic variables, which is used in the research and teaching process at the Chair of Spatial Econometrics at the University of Lodz. The study also presents suggestions for applying a time-series-crosssection data analysis method in forecasting employment structure in Poland in a regional cross-section (NUTS2). The results obtained indicate that these methods can be used in the forecasting process. The use of location quotient and shift-share analysis allows additional information, which may be used in time-series-cross-section data forecasting in a territorial crosssection. The analyses and forecasts on regional level are at present an inherent element of European Union policy, including measuring cohesion policy effectiveness.