This study uses data from the Ethiopia Demographic and Health Survey [ 2 0 05EDH S] conducted in 2005 to investigate the predictors of child [0-5 years] mortality in developing country like Ethiopia. The specific objectives of this study are to identify the factors which are affecting child mortality and to suggest viable strategies to increase health service and reduce child mortality in Ethiopia. The cross-tabulation technique has been used to estimate the predictors of child mortality. The cross-tabulation analysis shows that Birth Interval with Previous child and mother standard of living indexes the vital factor associated with child mortality. Furthermore, Mother’s education, birth order has substantial impact on child mortality in Ethiopia. Finally these findings specified that an increase in Mothers’ education, improve health care services which should in turn raise child survival and should decrease child mortality in Ethiopia.