< e purpose of the study is to give an overview of end-stage renal disease (ESRD) and
renal replacement therapy (RRT) in the Republic of Macedonia in a period of  years
(-). Data are collected by questionnaires for individual patients that are distributed
to  haemodialysis centres in the country. Incidence, prevalence, mean and
median age, primary renal disease, established therapy, number of renal transplants
per year and mortality are assessed and elaborated. < ere is an increase of incident patients
on RRT over the years, from , in  to , per million population in ,
on day , adjusted for age and gender. Mean age of incident patients is also increasing,
from ,±, at day  in , to ,±, in . Hypertension and diabetes are
increasing and have become the leading cause of renal failure in incident patients at
day , unadjusted, in  (, and , respectively). Prevalent counts on RRT are
also increasing, from , per million population in , adjusted for age and gender,
to , in . Glomerulonephritis and unknown cause of renal failure are the leading
cause of ESRD in prevalent patients. Haemodialysis is the predominant RRT modality
in Macedonia either for incident, or prevalent patients, and is around . < e
crude death rate on dialysis is relatively low, , in . Incidence and prevalence
on RRT are continuously increasing, and hypertension and diabetes are becoming the
leading cause of ESRD. Kidney transplantation is underrepresented and eff orts should
be undertaken for its increase.