Despite growing concerns over increasingly relaxed sexual culture in Vietnam, population-based research that investigates the openness to premarital sex in contemporary Vietnam remains scarce. Using data from the Vietnam Population and AIDS Indicator Survey 2005, this study examined the acceptance toward premarital sex and documented significant differences in attitudes by gender, age, and marital status. Attitudes of Vietnamese toward premarital sex generally remained conservative. Men were more permissive than women. Among both male and female respondents, higher acceptance levels were reported to men's practice of premarital sex than to women's same practice. Unmarried respondents were more open than those who were married. A growing openness toward premarital sex among the younger age was found only among the married. Results suggest the coexistence of traditional values and a growing permissiveness toward premarital sex in Vietnam.