The performance of the public health sector in Kenya has been a major concern to the Kenyan
people. Good health is a prerequisite for enhanced economic growth and poverty reduction and
a precursor to the realization of Kenya Vision 2030’s social pillar goal. The country is confronting
numerous gaps in health outcomes like high infant mortality rate caused by neonatal problems.
Therefore, the purpose of this study was to determine the influence of inventory management
practice and the performance of the unit of vaccines and immunizations in the Ministry of
Health, Kenya. The study adopted mixed research design using both quantitative and qualitative
approaches. The target population of the study was 244 from the Unit of Vaccine and
Immunizations (UVIS) headquarter KEMSA depot and warehouse staff, Nairobi, Mombasa,
Kisumu, and Busia counties. The study used random sampling to pick a sample size of 74
respondents. Data was collected using questionnaire. Descriptive statistics was used aided by
Statistical Packages for Social Sciences version 24 to compute percentages of respondents’
answers. Inferential statistics multiple regression analysis was applied to examine the
relationship between the research variables. The results showed that there is strong positive
correlation between inventory management and the performance of the unit of vaccines and
immunizations. Hence, buffer stock, optimal inventory level, collaborations with key
stakeholders, continuously monitor inventory levels, stocks transfer/replenishment orders and
procurement plan if adopted can improve the performance of the unit of vaccines and
immunizations.