Risk of polio reintroduction to border regions of Islamic Republic of Iran: seroprevalence study of children with at least 5 doses of oral polio vaccine

Type Journal Article - Eastern Mediterranean Health Journal
Title Risk of polio reintroduction to border regions of Islamic Republic of Iran: seroprevalence study of children with at least 5 doses of oral polio vaccine
Author(s)
Volume 20
Issue 5
Publication (Day/Month/Year) 2014
Page numbers 287-294
URL http://applications.emro.who.int/EMHJ/V20/05/EMHJ_2014_20_5_287_294.pdf
Abstract
Movements of populations from countries where polio has not been eradicated is a concern in the Islamic
Republic of Iran. A cross-sectional, community-based study was implemented in 2010 in 2 districts in Sistan-va-Baluchestan
Province near the south-east border. The aim was to determine the seroprevalence of antibodies in children aged 20 (±
2) months who had received at least 5 doses of trivalent oral polio vaccine. Using cluster sampling, 365 children were
enrolled for serological testing. Antibody titres = 1:10 were considered positive. Seropositive rates for antibody against
poliovirus serotypes 1, 2 and 3 were 94.1%, 96.7% and 78.3% respectively. The lowest seropositive rate was for antibody
against polio serotype 3 (PV3) among boys (58.3%). Exclusive breastfeeding showed a direct relationship with antibody
response to PV3 (OR = 2.0; 95% CI: 1.1–3.6). Improving community protection against PV3 is an urgent programme priority

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