The article seeks to determine, under the public policy approach, the main factors leading to the generation of an entrepreneurship policy in Colombia during 2002-2010, highlighting the role of Servicio Nacional de Aprendizaje (SENA) and universities. An exploratory-descriptive study was conducted, usingsource information (surveys and interviews with experts in the field), and secondary (multiple document review). Two main lessons were learned: 1) to generate an entrepreneurship policy is not a prerequisite to have a law or document that drives it, but with political will and clear vision of what is intended by the actors involved, and 2) government agencies leading its design and execution, as well as their managers, must have at least credence, experience and stability.