As the HIV/AIDS pandemic progresses, it is becoming apparent that heterosexual transmission represents the major mode of spread of HIV infection in most regions of the world, especially in Africa. The rapid spread of AIDS in Africa, therefore, indicates a high rate of heterosexual transmission. Possible factors contributing to the HIV epidemic in Africa include sexual behavior as influenced by pre-existing cultural attitudes and practices, ineffective disease control measures, or co-infection with other sexually transmitted diseases (STDs).