This study focuses on the changing practices of South African residents’ associations and their relationship with political parties and local government from 1990 to 2006, with the aim to examine how associations in Cape Town respond when they are confronted with a new democratic institutional and political context. Two empirical questions guide the analysis: How do residents’ associations perceive that the changing political context has affected them in their attempts to influence agenda-setting and decision-making? And how can we understand the process in which they decide to act, or not act, in response to important changes in their political environment? Drawing on social movement theory, most importantly the notions of political opportunity structures and framing processes, an analysis is made of the most significant changes in Cape Town’s post-apartheid institutional and political context. The empirical findings – based on questionnaires, interviews and an in-depth study of the township of Imizamo Yethu in Hout Bay – show that associations in socio-economically distinct areas have different perceptions of their prospects of affecting agenda-setting and decision-making. Because of the close links with political parties, many associations interpret the political and institutional changes as either threats or opportunities depending on which party controls the City Council. In predominantly white affluent areas associations generally seem to underestimate their chances of being influential, whereas those in black poor areas tend to overestimate their ability to influence decision-making when the ANC is in a government position.