To examine the time trend leukemia incidence rates by sex among age groups (0–19) and (20-=70), in Ninawa/Iraq. Beginning with the Iran–Iraq and ended with the end of USA occupation. We analyzed the data for cancer of all types of leukemia combined (ICD 9th, codes 204-8), between 1st January 1980 and 31st December 2010 were taken from annual book series published from the Directorate of Health in Ninawa-Mosul Continuing Medical Education Center. This data was collected from all hospitals in Ninawa Province by the Mosul Cancer Registry. Population data were collected from the Central Organization for Statistics, Ministry of Planning. A study found that males aged 0-19 years are more sensitive than females from the first shock when an extremely major events occur, while females of the same age, sensitivity to a precarious situation or perilous position. In the 20 – =70 years age group, the consequences of economic crises and war influenced among males more than females. The Psychological factors, where the intense fear and the high risk which threatened the individuals who more sensitive and vulnerable to the first shock was caused increase in the incidence rates, in addition to economic crises.