Karnataka is one among the states in India likely to be impacted seriously by climate change due to its heavy reliance on monsoon-dependent rain-fed agriculture (80% of cropland), frequent occurrence of drought and floods, monsoon-dependent seasonal flow of the rivers, large coastal fishing community and biodiversity-rich Western Ghats. Therefore, with the help of the current research work, we have developed district-wise vulnerability for a broader assessment of climate change impacts in Karnataka.