There have been significant public health achievements in recent years; not only do people live longer and healthier lives, but there has also been a decline in communicable diseases, like tuberculosis, and water-borne diseases, especially in developing countries like India. Although lifestylerelated problems are emerging globally, developing countries carry heavier burdens of poor health conditions, which is an issue of serious concern, in particular among marginalized populations. Reaching out to these groups is a global challenge, and particularly in India, where one-third of the population (between 250 and 300 million people) live in remote, difficult and vulnerable areas lacking basic amenities. In order to address the ‘health for all’ challenge, this Commentary advocates for the public, private and non-profit sectors to work together to implement innovative community-based approaches that address the various social determinants of health. The case of the Voluntary Health Association of India (VHAI), a national NGO, is presented as an example of successful coordinated community and policy actions to improve health determinants in remote rural areas of India. (Global Health Promotion, 2010; 17(1): pp. 69—72)