Contraception is one of the major determinants of fertility levels globally. The aim of this thesis were to determine the contraceptive use prevalence and determine the factors affecting contraceptive use among married women aged 18-45 years in WassaAmenfi West district.160 married women from the WassaAmenfi West District were purposively sampled and interviewed using structured questionnaires to obtain the data. Univariate, Bivariate and Multivariate analysis, specifically binary logistic model were employed in the study.The study results revealed that majority of the respondents were aged 28-35 years and they were predominantly Christians. We found significant association between the current use of contraceptives and the variables occupation, number of living children, freedom of taking decision, family planning discussion with husband, visits to family planning centers and the level of education of respondents using the Pearson Chi-square test. Finally, the logistic regression model showed that the current use of contraceptives among the married women of WassaAmenfi West district was strongly associated with their level of education and the discussion of family planning with husband. The estimated odds of using contraceptives among women with basic education, secondary education and tertiary were 3.406 times, 8.056 times and 8.125 times respectively the estimated odds for those with no education. Family planning discussion with husband showed a strong effect with odds ratio of 19.788 times the odds of those who never discussed family planning with husband. Clearly, the current use of contraceptives increases with increasing level of education of respondents and also substantially influenced by discussion of family planning with husbands.