Background: The HIV infection among adult male is high in Nepal. The chances of HIV infection from heterosexual route and infecting close partners are high due to their risky sexual behaviors. This study aimed to assess the risk of HIV Infection and risk factors associated with high risk of HIV infection among adult male in Nepal.

Methodology: An analytical cross-sectional study was conducted from the data of Nepal Demographic and Health Survey 2011. Out of 4121 adult men aged between (15-49) years interviewed in the survey, 2837 who had at least one sexual experience was included in the study. The risk of HIV infection was calculated using two sexual risk behaviors; multiple sex partners in last 12 months and condom used in last sexual intercourse. The univariate and multivariate analysis was done to assess the factors associated with high risk of HIV infection.

Results: About 4% of adult male have high risk of HIV infection in Nepal. The high risk of HIV infection was significantly associated with young age, middle wealth class, having paid for sex and being sexually active in last 4 weeks preceding the survey. Conclusion: There was substantial high risk of HIV infection among adult male in Nepal. The high risk and its associated factors needed a comprehensive response in order to reduce the risk.